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Tadalafil Softgel
Tadalista Super Active

  • Tadalafil Softgel
  • ED036
  • In Stock

Premium High Quality Product & Original Active Substance!

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   Manufacturer's Suggested Retail Price (MSRP) per pill is $5.97 ! Buying from us will save you at least 40.87%

Package per pill Price SAVINGS BONUS Order
20mg * 10 pills
$3.53 $35.30 $0.00
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SILVER BONUS
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20mg * 20 pills
$2.48 $49.60 $21.00
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SILVER BONUS
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20mg * 30 pills
$2.09 $62.70 $43.20
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SILVER BONUS
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20mg * 40 pills
$1.87 $74.80 $66.40
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SILVER BONUS
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20mg * 50 pills
$1.74 $87.00 $89.50
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SILVER BONUS
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20mg * 60 pills
$1.62 $97.20 $114.60
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SILVER BONUS
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20mg * 70 pills
$1.56 $109.20 $137.90
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SILVER BONUS
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20mg * 80 pills
$1.46 $116.80 $165.60
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SILVER BONUS
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20mg * 90 pills
$1.41 $126.90 $190.80
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SILVER BONUS
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20mg * 120 pills
$1.13 $135.60 $288.00
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SILVER BONUS
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20mg * 150 pills
$1.06 $159.00 $370.50
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SILVER BONUS
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20mg * 180 pills
$0.96 $172.80 $462.60
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SILVER BONUS
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Tadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor.

Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy.

Tadalafil tablets are indicated for the treatment of: erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), the signs and symptoms of BPH (ED/BPH).

Tadalista Super Active contain the active ingredient, tadalafil, in the gel-like form. From above they are covered with a soluble natural gelatin shell that does not irritate the stomach. Inside the active ingredient is in the liquefied state therefore it starts much faster to operate. Usually, after consuming the pills before the onset of an erection takes place 15-20 minutes. When severe psychological depression, extreme fatigue effect the appearance may be slightly delayed. 1 day permitted use not more than 1 capsule. The effect lasts for 24-36 hours.

Tadalafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum.

This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Tadalafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.

This means that, with tadalafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, tadalafil should not cause an erection.

Tadalafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle.

This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by tadalafil enhances erectile function by increasing the amount of cGMP.

Metabolism: Tadalafil is predominantly metabolized by CYP3A4 to a catechol metabolite. The catechol metabolite undergoes extensive methylation and glucuronidation to form the methylcatechol and methylcatechol glucuronide conjugate, respectively. In vitro data suggests the metabolites are not expected to be pharmacologically active at observed metabolite concentrations.

Absorption: After single oral-dose administration, the maximum observed plasma concentration (Cmax) of tadalafil is achieved between 30 minutes and 6 hours (median time of 2 hours). Absolute bioavailability of tadalafil following oral dosing has not been determined.

Route of elimination: Tadalafil is excreted predominantly as metabolites, mainly in the feces (approximately 61% of the dose) and to a lesser extent in the urine (approximately 36% of the dose).

Half life: 17.5 hours

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Tadalafil.

Tell your doctor or pharmacist if you have any medical conditions.

Common tadalafil side effects may include: headache, flushing (warmth, redness, or tingly feeling), nausea, upset stomach, stuffy nose; or muscle pain, back pain, pain in your arms or legs.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Chris
15/Aug/2024

I am a healthy 50 year old peace officer. Have tried Viagra and Levitra over the years with limited success. Recently a friend introduced me to Tadalista Super Active. All I can say is "where has this been all my life??" I take one 20mg pill at noon. I am ready, willing, and now, thanks to Tadalista Super Active, able, to perform almost immediately. I feel as I did when I was a teenager. My erections are often and much, much stronger and last so much longer. This has to be the Fountain of Youth! Sure feels that way to me and to my partner.

Dean
14/Aug/2024

So far, excellent and no issues. Had to split the pill in quarters, even half 2.5 was too much, felt like I was going to pop down there.

Naan
05/Aug/2024

Am 45 and have tried all three erectile dysfunction medicines. Sildenafil and Vardenafil both give me headaches. Tadalafil, however, gives me no side effects whatsoever, except of course for a great erection (even if I've been drinking). And it lasts for the 36 hours as advertised. Nice to be able to take one on Friday night and be good for the whole weekend.

Tom
05/Mar/2023

I am a 54 year old male. Can get erection without meds but when I take 20mg of Tadalista Super Active it works great. Get very hard, aroused easily throughout the day like I am a 20 year old. It is the only medication I take. Doing 20 mg a day but if I miss it lasts longer. Great for old guys makes me feel good about myself.

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